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Thiozonide

Currently in clinical development

Description:

A new innovative product has been developed. It exhibits a pronounced antiphthisic activity against mycobacteria, both virulent strains of M. tuberculosis and resistant to first-line treatments.

As well, it exhibits a bacteriostatic effect.

As expected, it blocks a specific bacterial enzyme, leading to impaired ATP synthesis in a M. tuberculosis cell. The active component is primarily metabolized via cytochrome P450 enzymes.

This drug product is currently in clinical development.